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APEX1 抗体 (N-Term)

APEX1 适用: 小鼠, 大鼠, Cow, 兔, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN183434
发货至: 中国
  • 抗原 See all APEX1 抗体
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 90
    • 43
    • 39
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠, Cow, 兔, 马, 豚鼠
    宿主
    • 74
    • 17
    • 2
    克隆类型
    • 76
    • 17
    多克隆
    标记
    • 64
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APEX1 antibody is un-conjugated
    应用范围
    • 80
    • 30
    • 28
    • 24
    • 18
    • 11
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MPKRGKKAAA DDGEEPKSEP ETKKSKGAAK KTEKEAAGEG PVLYEDPPDQ
    预测反应
    Cow: 85%, Guinea Pig: 86%, Horse: 79%, Mouse: 100%, Rabbit: 86%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against APEX1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product APEX1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 317 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    别名
    APEX1 (APEX1 产品)
    背景
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells.
    Alias Symbols: APE, Apex, HAP1, Ref-1
    Protein Interaction Partner: Pcna, Gadd45a, Eed, Mutyh, Plcb1, Hdac1, Sin3a, Hdac2,
    Protein Size: 317
    分子量
    35 kDa
    基因ID
    11792
    NCBI登录号
    NM_009687, NP_033817
    UniProt
    Q544Z7
    途径
    DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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