AHRR 抗体 (Middle Region)
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- 抗原 See all AHRR 抗体
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
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抗原表位
- Middle Region
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AHRR antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CLRGGPDLLD PKGTSGDREE EDQKHILRRS PGAWGQREMH KYSYGLETPV
- 预测反应
- Mouse: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Ahrr. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product AHRR Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 701 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
- 别名
- Ahrr (AHRR 产品)
- 别名
- mKIAA1234 antibody, AHH antibody, AHHR antibody, bHLHe77 antibody, ahh antibody, ahhr antibody, bhlhe77 antibody, ahrr2 antibody, aryl-hydrocarbon receptor repressor antibody, aryl hydrocarbon receptor repressor-like antibody, uncharacterized LOC723045 antibody, aryl-hydrocarbon receptor repressor L homeolog antibody, aryl hydrocarbon receptor repressor antibody, aryl-hydrocarbon receptor repressor b antibody, Ahrr antibody, AHRR antibody, LOC529500 antibody, LOC723045 antibody, ahrr.L antibody, LOC100455869 antibody, ahrr antibody, LOC100136487 antibody, ahrrb antibody
- 背景
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Ahrr mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Ahrr represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Ahrr represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Alias Symbols: KIAA1234, mKIAA1234
Protein Size: 701 - 分子量
- 78 kDa
- 基因ID
- 11624
- NCBI登录号
- NM_009644, NP_033774
- UniProt
- Q3U1U7
- 途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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