AIRE 抗体 (N-Term)
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- 抗原 See all AIRE 抗体
- AIRE (Autoimmune Regulator (AIRE))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AIRE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- HRTEIAVAVD SAFPLLHALA DHDVVPEDKF QETLHLKEKE GCPQAFHALL
- 预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against AIRE. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human AIRE
- Top Product
- Discover our top product AIRE Primary Antibody
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anti-Autoimmune Regulator (AIRE) (C-Term) antibody
Verified AIRE 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 30-130) antibodyAIRE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyAIRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyVerified AIRE 适用: 人, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 39-108) antibodyAIRE 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (pSer156) antibodyAIRE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 467-516) antibodyAIRE 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 218-267) antibodyAIRE 适用: 人, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) antibodyAIRE 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyAIRE 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 545 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- AIRE (Autoimmune Regulator (AIRE))
- 别名
- AIRE (AIRE 产品)
- 别名
- AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
- 背景
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The function of the protein encoded by the AIRE gene is not well defined. However it contains zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Alias Symbols: AIRE1, APECED, APS1, APSI, PGA1
Protein Interaction Partner: TUBB, RAVER1, TUBA1C, TMPRSS13, CCDC87, FAT1, GIGYF2, SRRM2, TUBB4B, EIF4EBP3, UBB, HSP90AB1, HSPA8, HSPA5, HSPA1L, HSPA1A, ATP4A, HIST3H3, HDAC2, HDAC1, DAXX, AIRE, UBAC1, HIST1H3A, HIST2H2BE, HSPA4, SRSF1, SMC1A, XPO1, TOP2A, SSRP1, SNRPD3, SNRPB, SRSF3
Protein Size: 545 - 分子量
- 58 kDa
- 基因ID
- 326
- NCBI登录号
- NM_000383, NP_000374
- UniProt
- O43918
- 途径
- Chromatin Binding
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