T-Bet 抗体 (Middle Region)
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- 抗原 See all T-Bet 抗体
- T-Bet
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This T-Bet antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- SIPSPPGPNC QFLGGDHYSP LLPNQYPVPS RFYPDLPGQA KDVVPQAYWL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against TBX21. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TBX21
- Top Product
- Discover our top product T-Bet Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 535 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- T-Bet
- 别名
- TBX21 (T-Bet 产品)
- 别名
- T-PET antibody, T-bet antibody, TBET antibody, TBLYM antibody, TBT1 antibody, Tbet antibody, Tblym antibody, T-box 21 antibody, TBX21 antibody, Tbx21 antibody
- 背景
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TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Alias Symbols: HGNC:11599, T-PET, T-bet, TBLYM, TBET
Protein Interaction Partner: USP10, UBC, EXOC5, ZNF490, SP1, HOXC11, GATA3, EP300, CREBBP,
Protein Size: 535 - 分子量
- 58 kDa
- 基因ID
- 30009
- NCBI登录号
- NM_013351, NP_037483
- UniProt
- Q9UL17
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