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HIPK2 抗体 (Middle Region)

HIPK2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779735
发货至: 中国
  • 抗原 See all HIPK2 抗体
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    抗原表位
    • 8
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 51
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马
    宿主
    • 46
    • 6
    克隆类型
    • 45
    • 7
    多克隆
    标记
    • 28
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIPK2 antibody is un-conjugated
    应用范围
    • 30
    • 26
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR
    预测反应
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%
    产品特性
    This is a rabbit polyclonal antibody against HIPK2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1198 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Upadhyay, Bhadauriya, Ganesh: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." in: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, (2016) (PubMed).

    Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." in: Oncogene, Vol. 28, Issue 26, pp. 2446-55, (2009) (PubMed).

    Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).

  • 抗原
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    别名
    HIPK2 (HIPK2 产品)
    别名
    HIPK2 antibody, cb1009 antibody, si:dkey-16j24.2 antibody, si:dkey-239k7.1 antibody, wu:fk56d12 antibody, pro0593 antibody, MGC146781 antibody, PRO0593 antibody, 1110014O20Rik antibody, B230339E18Rik antibody, Stank antibody, PKM antibody, homeodomain interacting protein kinase 2 antibody, serine/threonine kinase antibody, homeodomain interacting protein kinase 2 L homeolog antibody, HIPK2 antibody, Smp_000720 antibody, hipk2 antibody, hipk2.L antibody, Hipk2 antibody
    背景
    HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
    Alias Symbols: DKFZp686K02111, FLJ23711, PRO0593
    Protein Interaction Partner: UBC, TP53, SIAH2, XAF1, AATF, SUMO1, MDM2, AXIN1, SIAH1, MBP, DAXX, MKNK1, MECP2, ZBTB4, HIPK2, DCAF7, DYRK1B, MAP3K1, DYRK1A, FBXO3, CBX4, SUMO2, SUMO3, PML, PAX6, CHMP4B, SENP2, SENP1, UBE2I, HIST2H2BE, CXCL1, SIAH1P1, WSB1, MYBL2, MYBL1, NLK, MAP3K7, M
    Protein Size: 1198
    分子量
    120 kDa
    基因ID
    28996
    NCBI登录号
    NM_022740, NP_073577
    UniProt
    Q9H2X6
    途径
    Cell Division Cycle
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