WWTR1 抗体 (N-Term)
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- 抗原 See all WWTR1 抗体
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWTR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1
- Top Product
- Discover our top product WWTR1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 400 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- 别名
- WWTR1 (WWTR1 产品)
- 别名
- WWTR1 antibody, TAZ antibody, 2310058J06Rik antibody, 2610021I22Rik antibody, C78399 antibody, Taz antibody, WW domain containing transcription regulator 1 L homeolog antibody, WW domain containing transcription regulator 1 antibody, wwtr1.L antibody, wwtr1 antibody, WWTR1 antibody, Wwtr1 antibody
- 背景
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TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
Alias Symbols: DKFZP586I1419, TAZ
Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
Protein Size: 400 - 分子量
- 44 kDa
- 基因ID
- 25937
- NCBI登录号
- NM_015472, NP_056287
- UniProt
- Q9GZV5
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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