PTF1A 抗体 (N-Term)
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- 抗原 See all PTF1A 抗体
- PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTF1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PLEDGDELLA DEQAEVEFLS HQLHEYCYRD GACLLLQPAP PAAPLALAPP
- 预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 93%, Yeast: 75%
- 产品特性
- This is a rabbit polyclonal antibody against PTF1A. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PTF1A
- Top Product
- Discover our top product PTF1A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 328 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
- 别名
- PTF1A (PTF1A 产品)
- 背景
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PTF1A is a pancreas specific transcription factor. Mammalian studies have implicated important roles for the basic helix-loop-helix transcription factor PTF1A-p48 in the development of both exocrine and endocrine pancreas. This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PTF1-p48, bHLHa29
Protein Interaction Partner: TCF12,
Protein Size: 328 - 分子量
- 35 kDa
- 基因ID
- 256297
- NCBI登录号
- NM_178161, NP_835455
- UniProt
- Q7RTS3
- 途径
- Retinoic Acid Receptor Signaling Pathway
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