NCOR1 抗体 (N-Term)
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- 抗原 See all NCOR1 抗体
- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOR1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- NENYKALVRR NYGKRRGRNQ QIARPSQEEK VEEKEEDKAE KTEKKEEEKK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 85%
- 产品特性
- This is a rabbit polyclonal antibody against NCOR1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR1
- Top Product
- Discover our top product NCOR1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 2453 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))
- 别名
- NCOR1 (NCOR1 产品)
- 别名
- ncor antibody, zgc:56355 antibody, 5730405M06Rik antibody, A230020K14Rik antibody, N-CoR antibody, RIP13 antibody, Rxrip13 antibody, mKIAA1047 antibody, N-CoR1 antibody, TRAC1 antibody, hN-CoR antibody, nuclear receptor corepressor 1 antibody, nuclear receptor co-repressor 1 antibody, nuclear receptor corepressor 1 pseudogene antibody, nuclear receptor corepressor 1 S homeolog antibody, ncor1 antibody, NCOR1 antibody, CpipJ_CPIJ002507 antibody, LOC100343278 antibody, Ncor1 antibody, ncor1.S antibody
- 背景
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NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
Protein Interaction Partner: RARA, TP53, ESR1, PHB2, ZBTB16, THRB, THRA, CREB1, JUN, PPARG, SQSTM1, HDAC3, UBE2I, SOX2, HDAC7, HDAC5, HDAC4, UBC, SKIL, SKI, AR, SMAD4, CSNK2A1, RUNX1T1, CXADR, TBL1XR1, vif, C1D, CHUK, YWHAZ, SMARCE1, SMARCD1, SMARCA2, RBBP4, BPTF, HMGXB4, TAB2, NCOR2
Protein Size: 2453 - 分子量
- 270 kDa
- 基因ID
- 9611
- UniProt
- Q60974
- 途径
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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