SIRT4 抗体 (N-Term)
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- 抗原 See all SIRT4 抗体
- SIRT4 (Sirtuin 4 (SIRT4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 绵羊, 豚鼠, 山羊, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ASPPLDPEKV KELQRFITLS KRLLVMTGAG ISTESGIPDY RSEKVGLYAR
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SIRT4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT4
- Top Product
- Discover our top product SIRT4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 314 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SIRT4 (Sirtuin 4 (SIRT4))
- 别名
- SIRT4 (SIRT4 产品)
- 别名
- SIRT4 antibody, im:7139453 antibody, SIR2L4 antibody, 4930596O17Rik antibody, sirtuin 4 antibody, SIRT4 antibody, sirt4 antibody, Sirt4 antibody
- 背景
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SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Alias Symbols: MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4
Protein Interaction Partner: SKP2, Glud1, UBC, SIRT3, IDE, SLC25A6, SLC25A5,
Protein Size: 314 - 分子量
- 35 kDa
- 基因ID
- 23409
- NCBI登录号
- NM_012240, NP_036372
- UniProt
- Q9Y6E7
- 途径
- Negative Regulation of Hormone Secretion
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