SIRT1 抗体 (N-Term)
(5 references)-
- 抗原 See all SIRT1 抗体
- SIRT1 (Sirtuin 1 (SIRT1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 斑马鱼, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PETIPPPELD DMTLWQIVIN ILSEPPKRKK RKDINTIEDA VKLLQECKKI
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against SIRT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT1
- Top Product
- Discover our top product SIRT1 Primary Antibody
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anti-Sirtuin 1 (SIRT1) (AA 101-200) antibody
SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (AA 448-747) antibodySIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 566-601), (C-Term) antibodySIRT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB50965 unconjugated
anti-Sirtuin 1 (SIRT1) antibodySIRT1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Sirtuin 1 (SIRT1) antibodyKO Validated SIRT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 566-601) antibodySIRT1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 456-555) antibodySIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated
anti-Sirtuin 1 (SIRT1) (pSer47) antibodySIRT1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 1 (SIRT1) (AA 244-498) antibodySIRT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 747 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).
: "Butyric acid-induced rat jugular blood cytosolic oxidative stress is associated with SIRT1 decrease." in: Cell stress & chaperones, Vol. 19, Issue 2, pp. 295-8, (2014) (PubMed).
: "Changes in energy-regulated molecules in the trophocytes and fat cells of young and old worker honeybees (Apis mellifera)." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 69, Issue 8, pp. 955-64, (2014) (PubMed).
: "Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." in: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).
: "Risk assessment in patients with depressed left ventricular function after myocardial infarction using the myocardial performance index--Survival and Ventricular Enlargement (SAVE) experience." in: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Vol. 19, Issue 1, pp. 28-33, (2006) (PubMed).
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: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).
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- 抗原
- SIRT1 (Sirtuin 1 (SIRT1))
- 别名
- SIRT1 (SIRT1 产品)
- 别名
- sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
- 背景
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SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined,
Alias Symbols: SIR2L1
Protein Interaction Partner: SIRT2, KAT5, IRS1, ING2, ING1, HSP90AA1, AR, EP300, CDK1, CCNB1, RPS19BP1, KAT8, CLOCK, IRS2, UBE2I, TP53, STK11, WRN, PPARGC1A, FOXO1, VHL, UBC, E2F1, PSME3, KCNA5, KCNA4, KCNAB2, POP1, PPARA, CAP1, KIAA1598, TPM4, FASN, CDKL1, HIC1, HDAC4, CHD3, CDK6, S
Protein Size: 747 - 分子量
- 82 kDa
- 基因ID
- 23411
- NCBI登录号
- NM_012238, NP_036370
- UniProt
- Q96EB6
- 途径
- MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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