GLI1 抗体 (C-Term)
(8 references)-
- 抗原 See all GLI1 抗体
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TNPSCGHPEV GRLGGGPALY PPPEGQVCNP LDSLDLDNTQ LDFVAILDEP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against GLI1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GLI1
- Top Product
- Discover our top product GLI1 Primary Antibody
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anti-Zinc Finger Protein GLI1 (GLI1) (AA 601-700) antibody
GLI1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (cc), IHC (p), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 284-449) antibodyGLI1 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1B9F8 unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 401-500) antibodyGLI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 200-300) antibodyGLI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 805-820) antibodyGLI1 适用: 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibodyGLI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 921-1106) antibodyGLI1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 196-230) antibodyGLI1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54395 unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (C-Term) antibodyGLI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein GLI1 (GLI1) (AA 460-490) antibodyGLI1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1106 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Targeting Gli transcription activation by small molecule suppresses tumor growth." in: Oncogene, Vol. 33, Issue 16, pp. 2087-97, (2014) (PubMed).
: "WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function." in: Oncogene, Vol. 32, Issue 40, pp. 4737-47, (2013) (PubMed).
: "Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice." in: Human molecular genetics, Vol. 23, Issue 1, pp. 182-93, (2013) (PubMed).
: "Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development." in: Glia, Vol. 60, Issue 6, pp. 851-66, (2012) (PubMed).
: "In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines." in: International journal of cancer. Journal international du cancer, Vol. 131, Issue 2, pp. E33-44, (2012) (PubMed).
: "Up-regulation of sonic hedgehog contributes to TGF-?1-induced epithelial to mesenchymal transition in NSCLC cells." in: PLoS ONE, Vol. 6, Issue 1, pp. e16068, (2011) (PubMed).
: "Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells." in: Cancer letters, Vol. 310, Issue 2, pp. 222-31, (2011) (PubMed).
: "Signaling through the primary cilium affects glial cell survival under a stressed environment." in: Glia, Vol. 59, Issue 2, pp. 333-44, (2010) (PubMed).
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: "Targeting Gli transcription activation by small molecule suppresses tumor growth." in: Oncogene, Vol. 33, Issue 16, pp. 2087-97, (2014) (PubMed).
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- 抗原
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- 别名
- GLI1 (GLI1 产品)
- 别名
- GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
- 背景
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GLI1 is a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined, however, it may play a role in normal development gene transcription. Mouse mutation studies indicate possible involvement in human foregut malformation.
Alias Symbols: GLI
Protein Interaction Partner: TRIM42, GCC1, PRKAA2, VHL, FEM1B, CDK4, UBC, MYC, ITCH, NUMB, SUFU, RAI1, XBP1, HDAC2, HDAC1, STK36, DYRK1A, ZIC2, ZIC1, Sin3a, Shh, SAP18, Su(fu), Pias1,
Protein Size: 1106 - 分子量
- 118 kDa
- 基因ID
- 2735
- NCBI登录号
- NM_005269, NP_005260
- UniProt
- P08151
- 途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
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