RUVBL1 抗体 (N-Term)
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- 抗原 See all RUVBL1 抗体
- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 斑马鱼, 豚鼠, 马, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUVBL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KIEEVKSTTK TQRIASHSHV KGLGLDESGL AKQAASGLVG QENAREACGV
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RUVBL1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL1
- Top Product
- Discover our top product RUVBL1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 456 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
- 别名
- RUVBL1 (RUVBL1 产品)
- 别名
- rvb1 antibody, ecp54 antibody, tip49 antibody, nmp238 antibody, pontin antibody, tip49a antibody, xpontin antibody, pontin52 antibody, TIP49 antibody, wu:fd18e04 antibody, zpontin antibody, ECP54 antibody, INO80H antibody, NMP238 antibody, PONTIN antibody, Pontin52 antibody, RVB1 antibody, TIH1 antibody, TIP49A antibody, Tip49a antibody, 2510009G06Rik antibody, RuvB like AAA ATPase 1 antibody, RuvB-like 1 (E. coli) antibody, RuvB-like 1 antibody, RuvB like AAA ATPase 1 S homeolog antibody, RuvB-like AAA ATPase 1 antibody, RuvB-like protein 1 antibody, RUVBL1 antibody, ruvbl1 antibody, PVX_123295 antibody, Bm1_15605 antibody, ruvb1 antibody, ruvbl1.S antibody, Ruvbl1 antibody
- 背景
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RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex.
Alias Symbols: ECP54, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49A, INO80H, PONTIN
Protein Interaction Partner: RUVBL2, HUWE1, CEP250, RPAP3, UBC, NEDD8, SUMO1, RNF2, EED, rev, NEDD4, CDC42, IQGAP1, PARK2, FBXO6, USP49, FBXO46, FBXW4, RBM8A, TELO2, TTI1, URI1, RUVBL1, TRRAP, TUBA1A, TUBB, SMG9, UPF1, PRKDC, POLR2E, NCBP1, LMNA, HSPA4, SMG8, PIH1D1, PABPC1, SMG1, PA
Protein Size: 456 - 分子量
- 50 kDa
- 基因ID
- 8607
- NCBI登录号
- NM_003707, NP_003698
- UniProt
- Q9Y265
- 途径
- Telomere Maintenance
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