HNF1B 抗体 (N-Term)
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- 抗原 See all HNF1B 抗体
- HNF1B (HNF1 Homeobox B (HNF1B))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HNF1B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL
- 特异性
- 100 % specific to all three isoforms of HNF1B (61, 58, 45kD).
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B
- Top Product
- Discover our top product HNF1B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 399 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HNF1B (HNF1 Homeobox B (HNF1B))
- 别名
- HNF1B (HNF1B 产品)
- 背景
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Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
Protein Size: 399 - 分子量
- 45 kDa
- 基因ID
- 6928
- NCBI登录号
- NM_006481, NP_006472
- UniProt
- P35680
- 途径
- Hormone Transport, Stem Cell Maintenance, Tube Formation
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