ETV5 抗体 (N-Term)
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- 抗原 See all ETV5 抗体
- ETV5 (Ets Variant 5 (ETV5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ETV5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AQVPDDEQFV PDFQSDNLVL HAPPPTKIKR ELHSPSSELS SCSHEQALGA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against ETV5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ETV5
- Top Product
- Discover our top product ETV5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 510 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ETV5 (Ets Variant 5 (ETV5))
- 别名
- ETV5 (ETV5 产品)
- 别名
- ERM antibody, etv5 antibody, fj87h10 antibody, id:ibd5133 antibody, wu:fj87h10 antibody, zgc:55647 antibody, 1110005E01Rik antibody, 8430401F14Rik antibody, ETS variant 5 antibody, ets variant 5 antibody, ets variant 5a antibody, ETV5 antibody, Etv5 antibody, etv5a antibody
- 背景
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ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer
Alias Symbols: ERM
Protein Interaction Partner: RFWD2, HDAC11, DHRS7, SEZ6L2, SLC22A2, HOXD9, CYP3A5, CCR5, CISH, AMH, APP, BRCA1, ELAVL1, SUMO2, UBC, AR,
Protein Size: 510 - 分子量
- 58 kDa
- 基因ID
- 2119
- NCBI登录号
- NM_004454, NP_004445
- UniProt
- P41161
- 途径
- Synaptic Membrane, Skeletal Muscle Fiber Development
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