ESR2 抗体 (Middle Region)
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- 抗原 See all ESR2 抗体
- ESR2 (Estrogen Receptor 2 (ESR2))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 绵羊, Pig, 马, 犬, Cow, 兔, 豚鼠, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ESR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EYLCVKAMIL LNSSMYPLVT ATQDADSSRK LAHLLNAVTD ALVWVIAKSG
- 预测反应
- Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Sheep: 86%
- 产品特性
- This is a rabbit polyclonal antibody against ESR2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ESR2
- Top Product
- Discover our top product ESR2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 530 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ESR2 (Estrogen Receptor 2 (ESR2))
- 别名
- ESR2 (ESR2 产品)
- 别名
- ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
- 背景
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ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Alias Symbols: ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Protein Interaction Partner: PLSCR1, MEOX2, NOTCH2NL, RFX6, MMS19, BCAS2, NCOA1, RPS18, MRPS15, MRPS22, ZC3HAV1, PTCD3, EXOSC4, MRPS2, MED4, MRPS27, MRPS31, MED17, TRIM24, NRIP1, NCOA3, STAU1, SP1, PABPC5, MYLK2, RPS11, RPS4X, RPLP0, RPL36AL, PPP5C, HSPA8, ESR2, ESR1, ACTB, SRA1, ARI
Protein Size: 530 - 分子量
- 59 kDa
- 基因ID
- 2100
- NCBI登录号
- NM_001437, NP_001428
- UniProt
- Q92731
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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