我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

EGR1 抗体 (N-Term)

Name: EGR1 抗体 (N-Term)
SKU: ABIN2779517
Availability: OutOfStock

EGR1 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-EGR1 Antibody Titration: 1 ug/ml Positive Control: Jurkat cell lysate (EGR1 抗体 (N-Term))

Immunohistochemistry with Colon, myenteric plexus tissue at an antibody concentration of 5. (EGR1 抗体 (N-Term))

IHC

Rabbit Anti-EGR1 Antibody Catalog Number: ARP32241 Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4. (EGR1 抗体 (N-Term))

IHC

Rabbit Anti-EGR1 Antibody Catalog Number: ARP32241 Paraffin Embedded Tissue: Human Spleen Cellular Data: Spleen cells Antibody Concentration: 4. (EGR1 抗体 (N-Term))

IHC

4 images

(7 references)

产品编号 ABIN2779517

发货至: 中国

Datasheet as PDF

抗原 See all EGR1 抗体

EGR1 (Early Growth Response 1 (EGR1))
抗原表位
16

9

6

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
N-Term
适用
57

36

24

7

6

6

6

4

4

3

2

1

1

1
人, 小鼠, 大鼠, Cow, 马, 兔, Pig
宿主
50

10

1
兔
Compatible Secondaries
克隆类型
50

11
多克隆
标记
36

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This EGR1 antibody is un-conjugated
应用范围
50

23

17

13

13

10

8

7

6

5

5

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

DNYPKLEEMM LLSNGAPQFL GAAGAPEGSG SNSSSSSSGG GGGGGGGSNS

预测反应

Cow: 87%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human EGR1

Top Product

Discover our top product EGR1 Primary Antibody
anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6E8 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 23-43), (N-Term) antibody
EGR1 适用: 人, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 9-37) antibody
EGR1 适用: 人, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 9-37), (N-Term) antibody
EGR1 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB19179 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 401-453) antibody
EGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 282-433) antibody
EGR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-543) antibody
EGR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 211-320) antibody
EGR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated

anti-Early Growth Response 1 (EGR1) (AA 444-544) antibody
EGR1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E8 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 543 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Balakrishnan, Stykel, Touahri, Stratton, Biernaskie, Schuurmans: "Temporal Analysis of Gene Expression in the Murine Schwann Cell Lineage and the Acutely Injured Postnatal Nerve." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153256, (2016) (PubMed).

Ohata, Yamazaki, Kawai, Tsugawa, Tachikawa, Koinuma, Miyagawa, Kimoto, Nakayama, Namba, Yamamoto, Okano, Ozono, Michigami: "Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 7, pp. 1627-38, (2014) (PubMed).

Lane, Yu, Lackey, Chen, Marzluff, Cook: "Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins." in: PLoS ONE, Vol. 8, Issue 3, pp. e58456, (2013) (PubMed).

Revest, Kaouane, Mondin, Le Roux, Rougé-Pont, Vallée, Barik, Tronche, Desmedt, Piazza: "The enhancement of stress-related memory by glucocorticoids depends on synapsin-Ia/Ib." in: Molecular psychiatry, Vol. 15, Issue 12, pp. 1125, 1140-51, (2010) (PubMed).

Jaluria, Konstantopoulos, Betenbaugh, Shiloach: "Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates." in: Biotechnology and bioengineering, Vol. 99, Issue 6, pp. 1443-52, (2008) (PubMed).

Wenzel, Daskalow, Herse, Seitz, Zacharias, Schenk, Schulz, Hubner, Micheel, Schlag, Osterziel, Ozcelik, Scherneck, Jandrig: "Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway." in: Biological chemistry, Vol. 388, Issue 5, pp. 489-95, (2007) (PubMed).

Barbolina, Adley, Ariztia, Liu, Stack: "Microenvironmental regulation of membrane type 1 matrix metalloproteinase activity in ovarian carcinoma cells via collagen-induced EGR1 expression." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4924-31, (2007) (PubMed).
抗原

EGR1 (Early Growth Response 1 (EGR1))

别名

EGR1 (EGR1 产品)

别名

AT225 antibody, G0S30 antibody, KROX-24 antibody, NGFI-A antibody, TIS8 antibody, ZIF-268 antibody, ZNF225 antibody, A530045N19Rik antibody, ETR103 antibody, Egr-1 antibody, Krox-1 antibody, Krox-24 antibody, Krox24 antibody, NGF1-A antibody, NGFIA antibody, Zenk antibody, Zfp-6 antibody, Zif268 antibody, egr antibody, Ngf1 antibody, Ngfi antibody, zif-268 antibody, EGR1 antibody, EGR-1-A antibody, Xegr-1 antibody, at225 antibody, egr-1 antibody, egr1 antibody, g0s30 antibody, krox-24 antibody, ngfi-a antibody, tis8 antibody, znf225 antibody, krox24 antibody, wu:fj64b05 antibody, wu:fq25f01 antibody, EGR-1 antibody, zenk antibody, EGR-1-B antibody, egr1-a antibody, egr1-b antibody, early growth response 1 antibody, early growth response protein 1 (egr-1) antibody, early growth response 1 L homeolog antibody, early growth response 1 S homeolog antibody, EGR1 antibody, CNK00890 antibody, Egr1 antibody, egr1.L antibody, egr1 antibody, egr1.S antibody

背景

Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225
Protein Interaction Partner: CEBPB, WT1, SUMO1, TP53, MDM2, EP300, CDKN2A, SRA1, IL1B, PTEN, SP1, SNAI1, TBX2, PFDN5, SREBF2, ERBB3, NAB2, PITX1, NAB1, NFATC2, CREBBP, PSMA3, JUN, RELA, CSNK2A1, NFATC1, GADD45B, GADD45A,
Protein Size: 543

分子量

57 kDa

基因ID

1958

NCBI登录号

NM_001964, NP_001955

UniProt

P18146

途径

Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity