MTF1 抗体 (C-Term)
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- 抗原 See all MTF1 抗体
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MTF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MTF1
- Top Product
- Discover our top product MTF1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 753 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
- 别名
- MTF1 (MTF1 产品)
- 别名
- MTF-1 antibody, MTF1 antibody, mtf1 antibody, MGC86485 antibody, Thyls antibody, ZRF antibody, metal regulatory transcription factor 1 antibody, metal-regulatory transcription factor 1 antibody, metal-regulatory transcription factor 1 L homeolog antibody, metal response element binding transcription factor 1 antibody, MTF1 antibody, mtf1 antibody, mtf1.L antibody, Mtf1 antibody
- 背景
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The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
Alias Symbols: ZRF, MTF-1
Protein Interaction Partner: AP1M1, EP300, CREBBP, MT1G,
Protein Size: 753 - 分子量
- 81 kDa
- 基因ID
- 4520
- NCBI登录号
- NM_005955, NP_005946
- UniProt
- Q14872
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