LMX1A 抗体 (Middle Region)
Quick Overview for LMX1A 抗体 (Middle Region) (ABIN2779408)
抗原
See all LMX1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- QNQRAKMKKL ARRQQQQQQD QQNTQRLSSA QTNGGGSAGM EGIMNPYTAL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LMX1A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human LMX1A
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anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 9-86) antibody
LMX1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 303-337), (C-Term) antibodyLMX1A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50873 unconjugated
anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 244-293) antibodyLMX1A 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 301-350) antibodyLMX1A 适用: 小鼠, 大鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (AA 251-300) antibodyLMX1A 适用: 小鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, alpha (LMX1A) (N-Term) antibodyLMX1A 适用: 人, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 382 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
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别名
- LMX1A
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背景
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Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
Alias Symbols: LMX-1, LMX1, LMX1.1, MGC87616
Protein Interaction Partner: LDB1, BMPR2, ISL1, LHX3, LMX1A, TCF3,
Protein Size: 382 -
分子量
- 43 kDa
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基因ID
- 4009
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NCBI登录号
- NM_177398, NP_796372
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UniProt
- Q8TE12
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途径
- Dopaminergic Neurogenesis
抗原
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