IRF6 抗体 (Middle Region)
(1 reference)-
- 抗原 See all IRF6 抗体
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠, 绵羊, 斑马鱼, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRF6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- IPVVARMIYE MFSGDFTRSF DSGSVRLQIS TPDIKDNIVA QLKQLYRILQ
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against IRF6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human IRF6
- Top Product
- Discover our top product IRF6 Primary Antibody
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anti-Interferon Regulatory Factor 6 (IRF6) antibody
IRF6 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) antibodyIRF6 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (C-Term) antibodyVerified IRF6 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (AA 150-445) antibodyIRF6 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) antibodyIRF6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1A1 unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (AA 43-285) antibodyIRF6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (AA 1-467) antibodyIRF6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (AA 395-444) antibodyIRF6 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 绵羊, 斑马鱼, Pig, 猴, Hamster, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (C-Term) antibodyIRF6 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 6 (IRF6) (AA 196-445) antibodyIRF6 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 467 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." in: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
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: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." in: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
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- 抗原
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- 别名
- IRF6 (IRF6 产品)
- 别名
- IRF6 antibody, lps antibody, pit antibody, pps antibody, vws antibody, ofc6 antibody, xIRF-6 antibody, DKFZp469E012 antibody, LPS antibody, OFC6 antibody, PIT antibody, PPS antibody, PPS1 antibody, VWS antibody, VWS1 antibody, zgc:63500 antibody, AI876454 antibody, E230028I05Rik antibody, mirf6 antibody, interferon regulatory factor 6 antibody, interferon regulatory factor 6 S homeolog antibody, IRF6 antibody, irf6 antibody, irf6.S antibody, Irf6 antibody
- 背景
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IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1
Protein Interaction Partner: HHV8GK18_gp81, UBC, BNC2, IRF5, IRF8, ZBTB3, RFX3, TLX2, LBP,
Protein Size: 467 - 分子量
- 53 kDa
- 基因ID
- 3664
- NCBI登录号
- NM_006147, NP_006138
- UniProt
- O14896
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