IRF3 抗体 (C-Term)
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- 抗原 See all IRF3 抗体
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 绵羊, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SWPQDQPWTK RLVMVKVVPT CLRALVEMAR VGGASSLENT VDLHISNSHP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against IRF3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRF3
- Top Product
- Discover our top product IRF3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 427 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
- 别名
- IRF3 (IRF3 产品)
- 别名
- irf3 antibody, IRF3 antibody, C920001K05Rik antibody, IRF-3 antibody, interferon regulatory factor 3 antibody, interferon regulatory factor 7 antibody, irf3 antibody, IRF3 antibody, irf-3 antibody, Irf3 antibody, IRF7 antibody
- 背景
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IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: IRF3, UBC, TMEM173, POLR2A, DEAF1, CREBBP, MAFB, vIRF-3, SMAD4, SMAD2, FOXO1, vIRF-1, EP300, SGTA, PEX19, HSP90AA1, PIAS4, TBK1, TOMM70A, TLR2, MAPK9, MAPK8, MAVS, DDX58, TRAF3, ISG15, TRIM21, PIN1, IRF7, HERC5, IKBKE, CUL1, SUMO2, XIAP, HDAC3, SOCS1, RBL
Protein Size: 427 - 分子量
- 47 kDa
- 基因ID
- 3661
- NCBI登录号
- NM_001571, NP_001562
- UniProt
- Q14653
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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