PDX1 抗体 (N-Term)
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- 抗原 See all PDX1 抗体
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LYMGRQPPPP PPPQFTSSLG SLEQGSPPDI SPYEVPPLAS DDPAGAHLHH
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Pdx1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product PDX1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 284 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- 别名
- Pdx1 (PDX1 产品)
- 别名
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- 背景
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Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
Alias Symbols: IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
Protein Interaction Partner: Pcif1, Meis1, Hdac1, Hdac2, Ins1, Iapp, Spop, Pax4,
Protein Size: 284 - 分子量
- 31 kDa
- 基因ID
- 18609
- NCBI登录号
- NM_008814, NP_032840
- UniProt
- P52946
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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