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CXCR4 抗体 (N-Term)

CXCR4 适用: 人, 小鼠, 兔, Pig, 马 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779387
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗原表位
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    N-Term
    适用
    • 131
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    人, 小鼠, 兔, Pig, 马
    宿主
    • 112
    • 22
    • 10
    • 5
    • 1
    克隆类型
    • 120
    • 30
    多克隆
    标记
    • 96
    • 7
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 110
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    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    序列
    MEGISIYTSD NYTEEMGSGD YDSMKEPCFR EENANFNKIF LPTIYSIIFL
    预测反应
    Horse: 89%, Human: 91%, Mouse: 77%, Pig: 91%, Rabbit: 85%, Rat: 77%
    产品特性
    This is a rabbit polyclonal antibody against CXCR4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 352 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    背景
    CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
    Protein Interaction Partner: UBC, ITCH, nef, P4HB, CD4, env, MYBL2, ST13, ATP13A2, CXCL12, PTPN11, STAM, CAV1, SUMO4, HLA-C, SDC4, HSPA8, GNA13, STAT5B, SOCS3, SOCS1, CCR5, PTK2, STAT2, STAT1, JAK3, DPP4, PTPN6, VAV1, CXCR4, MYH9, PTPRC, JAK2, JAK1, GNAI1, ELANE, CTSG, ADRBK2, ARRB2,
    Protein Size: 352
    分子量
    40 kDa
    基因ID
    7852
    NCBI登录号
    NM_003467, NP_003458
    UniProt
    P61073
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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