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CLK4 抗体 (N-Term)

CLK4 适用: 小鼠, 人, 兔, 犬, 豚鼠, Cow, 马, 大鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779361
发货至: 中国
  • 抗原 See all CLK4 抗体
    CLK4 (CDC-Like Kinase 4 (CLK4))
    抗原表位
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 30
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 人, 兔, 犬, 豚鼠, Cow, 马, 大鼠, Saccharomyces cerevisiae
    宿主
    • 31
    • 1
    克隆类型
    • 32
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLK4 antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%
    产品特性
    This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
    Top Product
    Discover our top product CLK4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 481 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

  • 抗原
    CLK4 (CDC-Like Kinase 4 (CLK4))
    别名
    CLK4 (CLK4 产品)
    别名
    AI987988 antibody, C85119 antibody, zgc:112975 antibody, CDC like kinase 4 antibody, CDC-like kinase 4 antibody, CDC-like kinase 4b antibody, CLK4 antibody, Clk4 antibody, clk4b antibody
    背景
    The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
    Alias Symbols: DKFZp686A20267
    Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
    Protein Size: 481
    分子量
    57 kDa
    基因ID
    57396
    NCBI登录号
    NM_020666, NP_065717
    UniProt
    Q9HAZ1
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