FASL 抗体 (Middle Region)
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- 抗原 See all FASL 抗体
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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抗原表位
- Middle Region
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适用
- 人, Pig, Cow, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FASL antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MHTASSLEKQ IGHPSPPPEK KELRKVAHLT GKSNSRSMPL EWEDTYGIVL
- 预测反应
- Cow: 86%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 90%
- 产品特性
- This is a rabbit polyclonal antibody against FASLG. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product FASL Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 281 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- 别名
- FASLG (FASL 产品)
- 背景
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TNFSF6 is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Alias Symbols: APT1LG1, CD178, CD95L, FASL, TNFSF6, CD95-L
Protein Interaction Partner: RGS20, TRIP6, NOTCH2NL, KRT40, FAS, CFLAR, FADD, CASP8, NCF1, MACC1, SH3PXD2B, SNX33, SH3RF2, RIMBP3C, SNX18, EPS8L3, ARHGAP9, SAMSN1, MPP4, SRGAP1, BAIAP2L1, NCKIPSD, SNX9, MYO15A, ITSN2, TJP3, OSTF1, SRGAP2, DNMBP, SORBS3, SRGAP3, DOCK4, SH3PXD2A, KALRN
Protein Size: 281 - 分子量
- 31 kDa
- 基因ID
- 356
- NCBI登录号
- NM_000639, NP_000630
- UniProt
- P48023
- 途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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