TYK2 抗体 (C-Term)
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- 抗原 See all TYK2 抗体
- TYK2 (Tyrosine Kinase 2 (TYK2))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HRDLAARNVL LDNDRLVKIG DFGLAKAVPE GHEYYRVRED GDSPVFWYAP
- 预测反应
- Cow: 91%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TYK2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TYK2
- Top Product
- Discover our top product TYK2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1187 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TYK2 (Tyrosine Kinase 2 (TYK2))
- 别名
- TYK2 (TYK2 产品)
- 别名
- JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
- 背景
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Alias Symbols: JTK1
Protein Interaction Partner: KHDRBS2, KRT40, TRAF4, HNRNPK, FHL3, COPS5, JAK3, UBC, HSP90AA1, TYK2, PTAFR, EIF2AK2, LNX1, KLF10, SOCS1, TK1, DNM2, IFNAR1, JAKMIP1, XRCC5, STAM2, PRMT5, IFNAR2, CRKL, GHR, IRS2, IL6ST, STAT2, STAT1, IL13RA1, GNB2L1, PTPN1, PTPN6, PDGFRB, PLAUR, PIK3R1,
Protein Size: 1187 - 分子量
- 134 kDa
- 基因ID
- 7297
- NCBI登录号
- NM_003331, NP_003322
- UniProt
- P29597
- 途径
- JAK/STAT Signaling, Hepatitis C
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