RNP 抗体 (Middle Region)
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- 抗原 See all RNP (RNPC3) 抗体
- RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 马, Pig, 兔, Saccharomyces cerevisiae, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LHAPLPPTSP QPPEEPPLPD EDEELSSEES EYESTDDEDR QRMNKLMELA
- 预测反应
- Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 92%, Rat: 85%, Yeast: 77%
- 产品特性
- This is a rabbit polyclonal antibody against RNPC3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RNPC3
- Top Product
- Discover our top product RNPC3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 517 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
- 别名
- RNPC3 (RNPC3 产品)
- 别名
- rnp antibody, rbm40 antibody, zgc:136847 antibody, RBM40 antibody, RNP antibody, SNRNP65 antibody, 2810441O16Rik antibody, AI447568 antibody, C030014B17Rik antibody, RNA binding region (RNP1, RRM) containing 3 antibody, RNA-binding region (RNP1, RRM) containing 3 antibody, RNPC3 antibody, rnpc3 antibody, Rnpc3 antibody
- 背景
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RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
Protein Interaction Partner: SMAD2, CPSF1, CDK19, RPS3A, APP, PRNP, RNU11, RNU12-2P,
Protein Size: 517 - 分子量
- 58 kDa
- 基因ID
- 55599
- NCBI登录号
- NM_017619, NP_060089
- UniProt
- Q96LT9
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