RENT2/UPF2 抗体 (N-Term)
-
- 抗原 See all RENT2/UPF2 (UPF2) 抗体
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
-
抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠, 马, Pig, Cow, Saccharomyces cerevisiae, 斑马鱼, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RENT2/UPF2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- KAPEDKKKRL EDDKRKKEDK ERKKKDEEKV KAEEESKKKE EEEKKKHQEE
- 预测反应
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%, Yeast: 86%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against UPF2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human UPF2
- Top Product
- Discover our top product UPF2 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1272 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- 别名
- UPF2 (UPF2 产品)
- 别名
- HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
- 背景
-
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
Alias Symbols: DKFZp434D222, HUPF2, KIAA1408, MGC138834, MGC138835, RENT2, smg-3
Protein Interaction Partner: PUF60, UBC, UPF1, LGR4, MIF, LDHA, KRT18, ITGB1, HMGA1, ZBTB48, HBZ, ENO1, E4F1, CYBA, CALR, BLM, ATP1B3, ART4, DCP1B, DCP2, COMTD1, EXOSC6, GADD45GIP1, ZGPAT, MAP1LC3B, ZNF408, CENPU, WNK1, RSRC2, MRPL40, ZNF44, EXOSC1, MTERF3, GLTSCR2, NOB1, RRP7A, SERB
Protein Size: 1272 - 分子量
- 148 kDa
- 基因ID
- 26019
- NCBI登录号
- NM_015542, NP_056357
- UniProt
- Q9HAU5
-