IRAK3 抗体 (C-Term)
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- 抗原 See all IRAK3 抗体
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRAK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NTLESTQASL YFAEDPPTSL KSFRCPSPLF LENVPSIPVE DDESQNNNLL
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against IRAK3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK3
- Top Product
- Discover our top product IRAK3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 596 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
- 别名
- IRAK3 (IRAK3 产品)
- 背景
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IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Alias Symbols: ASRT5, IRAKM
Protein Interaction Partner: CDCA5, NSA2, LDB1, NTRK3, NONO, HSP90AA1, HOXB7, FOLR1, ECM1, COPB1, CD14, ATP6V0B, ADH1B, IRAK1, UBC, IRAK4, IRAK2, TICAM2, IRAK3, TRAF6, MYD88,
Protein Size: 596 - 分子量
- 66 kDa
- 基因ID
- 11213
- NCBI登录号
- NM_007199, NP_009130
- UniProt
- Q9Y616
- 途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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