PRPF8 抗体 (N-Term)
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- 抗原 See all PRPF8 抗体
- PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRPF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SHRHSVKSQE PLPDDDEEFE LPEFVEPFLK DTPLYTDNTA NGIALLWAPR
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PRPF8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF8
- Top Product
- Discover our top product PRPF8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 2335 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
- 别名
- PRPF8 (PRPF8 产品)
- 别名
- id:ibd1257 antibody, ik:tdsubc_2a9 antibody, im:7141966 antibody, tdsubc_2a9 antibody, wu:fb37c02 antibody, wu:fb73e06 antibody, xx:tdsubc_2a9 antibody, zgc:56504 antibody, hprp8 antibody, prp-8 antibody, prp8 antibody, prpc8 antibody, rp13 antibody, HPRP8 antibody, PRP8 antibody, PRPC8 antibody, RP13 antibody, SNRNP220 antibody, AU019467 antibody, D11Bwg0410e antibody, DBF3/PRP8 antibody, Prp8 antibody, Sfprp8l antibody, pre-mRNA processing factor 8 antibody, pre-mRNA processing factor 8 S homeolog antibody, Prpf8 antibody, prpf8 antibody, prpf8.S antibody, PRPF8 antibody
- 背景
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Pre-mRNA splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HPRP8, PRP8, PRPC8, RP13
Protein Interaction Partner: SNRNP200, PRPF8, EFTUD2, UBC, CDKN1A, SUMO2, SUMO3, STAU1, LGR4, NEDD8, ERG, ASB15, WWOX, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, rev, PIN1, NEDD4, FBXO6, PRPF4B, UBD, IGSF8, ICAM1, SND1, SF3B2, SLU7, ZNF830, WDR83, PRPF19, GPKOW, FN1, BCAS2, SF3B4, RBM5, VCA
Protein Size: 2335 - 分子量
- 273 kDa
- 基因ID
- 10594
- NCBI登录号
- NM_006445, NP_006436
- UniProt
- Q6P2Q9
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