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NXF1 抗体 (N-Term)

NXF1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778976
发货至: 中国
  • 抗原 See all NXF1 抗体
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    抗原表位
    • 13
    • 12
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 57
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 兔, 马
    宿主
    • 57
    • 1
    克隆类型
    • 49
    • 9
    多克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NXF1 antibody is un-conjugated
    应用范围
    • 40
    • 22
    • 19
    • 10
    • 9
    • 7
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RPNRRGDTWH DRDRIHVTVR RDRAPPERGG AGTSQDGTSK NWFKITIPYG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against NXF1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NXF1
    Top Product
    Discover our top product NXF1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 619 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NXF1 (Nuclear RNA Export Factor 1 (NXF1))
    别名
    NXF1 (NXF1 产品)
    别名
    im:7156527 antibody, wu:fc12d06 antibody, MGC82224 antibody, NXF1 antibody, tap antibody, mex67 antibody, MEX67 antibody, TAP antibody, Mex67 antibody, Mvb1 antibody, Tap antibody, Mex67h antibody, nuclear RNA export factor 1 antibody, nuclear RNA export factor 1 S homeolog antibody, Nuclear RNA export factor 1 antibody, nxf1 antibody, nxf1.S antibody, NXF1 antibody, LOC100113601 antibody, Tsp_03999 antibody, Nxf1 antibody, nxf-1 antibody
    背景
    NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
    Alias Symbols: DKFZp667O0311, MEX67, TAP
    Protein Interaction Partner: KRT40, TIFA, GFAP, LDOC1, NUP62, MID2, TP53BP2, DVL3, SUMO2, UBC, SUZ12, EED, BMI1, TARDBP, NXT1, NUP98, RANBP2, ESRRA, KCTD5, TRA2A, SGTA, TRA2B, SRSF1, RAD51, ZBED2, CSNK2A1, EIF2A, ILF3, HNRNPC, HNRNPK, DHX15, DHX9, DDB1, DDX19A, LUC7L3, HP1BP3, RBMX,
    Protein Size: 619
    分子量
    68 kDa
    基因ID
    10482
    NCBI登录号
    NM_006362, NP_006353
    UniProt
    Q9UBU9
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