Snurportin 1 抗体 (Middle Region)
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- 抗原 See all Snurportin 1 (SNUPN) 抗体
- Snurportin 1 (SNUPN)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 马, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Snurportin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GVAVPAGPLT TKPDYAGHQL QQIMEHKKSQ KEGMKEKLTH KASENGHYEL
- 预测反应
- Cow: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SNUPN. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SNUPN
- Top Product
- Discover our top product SNUPN Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 360 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Snurportin 1 (SNUPN)
- 别名
- SNUPN (SNUPN 产品)
- 背景
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: KPNBL, RNUT1, Snurportin1
Protein Interaction Partner: UBC, HOTAIR, MEX3B, XPO1, GCNT3, RNF126, DBN1, RPL17, KPNB1, PAFAH1B2, TNNT3, PEX5, ENO2, RAN, DDX20, ZPR1, SNRPB, SMN1,
Protein Size: 360 - 分子量
- 41 kDa
- 基因ID
- 10073
- NCBI登录号
- NM_005701, NP_005692
- UniProt
- O95149
- 途径
- Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus
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