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HNRPDL 抗体 (C-Term)

HNRPDL 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778938
发货至: 中国
  • 抗原 See all HNRPDL 抗体
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 33
    • 33
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔
    宿主
    • 48
    克隆类型
    • 48
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HNRPDL antibody is un-conjugated
    应用范围
    • 36
    • 21
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB)
    序列
    YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against HNRPDL. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPDL
    Top Product
    Discover our top product HNRPDL Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 420 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Johansson, Glahder, Mossberg, Schwartz: "Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs." in: Nucleic acids research, Vol. 41, Issue 22, pp. 10488-508, (2013) (PubMed).

    Anderson, Lin, Xiao, Stoilov, Burge, Black: "The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B." in: RNA (New York, N.Y.), Vol. 18, Issue 5, pp. 1041-9, (2012) (PubMed).

  • 抗原
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    别名
    HNRPDL (HNRPDL 产品)
    别名
    wu:fa11d08 antibody, zgc:66169 antibody, hnRNP DL antibody, Hnrpdl antibody, AA407431 antibody, AA959857 antibody, D5Ertd650e antibody, D5Wsu145e antibody, JKTBP antibody, hnRNP-DL antibody, hnRNP antibody, hnrpdl antibody, hnrpdl-a antibody, jktbp antibody, jktbp2 antibody, laauf1 antibody, HNRNP antibody, HNRPDL antibody, JKTBP2 antibody, laAUF1 antibody, hnRNP D-like B antibody, hnRNP DL-B antibody, hnrnpdl-b antibody, hnrpdl-b antibody, heterogeneous nuclear ribonucleoprotein D-like antibody, heterogeneous nuclear ribonucleoprotein D like antibody, heterogeneous nuclear ribonucleoprotein D like L homeolog antibody, heterogeneous nuclear ribonucleoprotein D like S homeolog antibody, hnrpdl antibody, HNRNPDL antibody, Hnrnpdl antibody, hnrnpdl.L antibody, LOC100351670 antibody, LOC101120922 antibody, hnrnpdl.S antibody
    背景
    HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.
    Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL
    Protein Interaction Partner: SPRTN, SUMO2, SUMO3, UBC, RPA3, RPA2, RPA1, ERG, EED, RNF2, rev, PARK2, FBXO6, TARDBP, HMGA1, ITGA4, IL7R, IFIT3, IFIT2, FN1, CSNK2A1, BARD1, EEF2, EEF1A1, DDX3X, ATP6V1B1, HNRNPA3, WIPF2, RMDN3, MRPS16, UBE2S, LSM14A, RPL36, U2AF2, HNRNPUL1, HNRNPA0, HNR
    Protein Size: 420
    分子量
    46 kDa
    基因ID
    9987
    NCBI登录号
    NM_005463, NP_005454
    UniProt
    O14979
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