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SSB 抗体 (N-Term)

Name: SSB 抗体 (N-Term)
SKU: ABIN2778846
Availability: OutOfStock

SSB 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Host: Rabbit Target Name: SSB Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2. (SSB 抗体 (N-Term))

nti-SSB Antibody IHC staining of human liver. (SSB 抗体 (N-Term))

IHC (p)

WB Suggested Anti-SSB Antibody Titration: 0. (SSB 抗体 (N-Term))

Rabbit Anti-SSB Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (SSB 抗体 (N-Term))

IHC

Immunohistochemistry with Human Prostate lysate tissue at an antibody concentration of 5. (SSB 抗体 (N-Term))

IHC

Rabbit Anti-SSB Antibody Paraffin Embedded Tissue: Human cardiac cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (SSB 抗体 (N-Term))

IHC

6 images

(1 reference)

产品编号 ABIN2778846

发货至: 中国

Datasheet as PDF

抗原 See all SSB 抗体

SSB (Sjogren Syndrome Antigen B (SSB))
抗原表位
15

9

9

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1
N-Term
适用
80

17

15

10

5

5

4

4

3

3

3

2

1

1

1
人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠
宿主
72

12

5
兔
Compatible Secondaries
克隆类型
79

10
多克隆
标记
49

6

6

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This SSB antibody is un-conjugated
应用范围
41

34

21

15

13

13

12

8

6

3

2

2

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

ISEDKTKIRR SPSKPLPEVT DEYKNDVKNR SVYIKGFPTD ATLDDIKEWL

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against SSB. It was validated on Western Blot and immunohistochemistry.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SSB

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anti-Sjogren Syndrome Antigen B (SSB) antibody
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anti-Sjogren Syndrome Antigen B (SSB) (AA 166-408) antibody
SSB 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (AA 1-408) antibody
SSB 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (AA 1-408) antibody
SSB 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1D6-H5 unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (AA 66-96) antibody
SSB 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (AA 82-131) antibody
SSB 适用: 人, 小鼠, 大鼠, 犬, 猴, 兔, 马, Cow, 豚鼠, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (AA 66-96), (N-Term) antibody
SSB 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17351 unconjugated

anti-Sjogren Syndrome Antigen B (SSB) antibody
SSB 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sjogren Syndrome Antigen B (SSB) (Ser366) antibody
SSB 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 408 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Teplova, Yuan, Phan, Malinina, Ilin, Teplov, Patel: "Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen." in: Molecular cell, Vol. 21, Issue 1, pp. 75-85, (2006) (PubMed).
抗原

SSB (Sjogren Syndrome Antigen B (SSB))

别名

SSB (SSB 产品)

别名

LARP3 antibody, La antibody, lab1 antibody, larp3 antibody, ssb antibody, Mt-SSB antibody, MtSSB antibody, Ssbp1 antibody, SS-B antibody, laa-a antibody, ssb-a antibody, ssb-b antibody, wu:fb17f11 antibody, zgc:55588 antibody, Sjogren syndrome antigen B antibody, Sjogren syndrome antigen B L homeolog antibody, single stranded DNA binding protein 1 antibody, Sjogren syndrome antigen B S homeolog antibody, Sjogren syndrome antigen B (autoantigen La) antibody, SSB antibody, ssb.L antibody, SSBP1 antibody, Ssb antibody, ssb.S antibody, ssb antibody

背景

SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006).[supplied by OMIM].
Alias Symbols: La, LARP3
Protein Interaction Partner: HUWE1, UBC, MDM2, LIN28A, BMI1, SUZ12, RNF2, rev, NPLOC4, DNM1L, UBA2, ANP32A, VBP1, RABGGTA, PPP2CA, KARS, CTTN, TARDBP, SOX2, HMGA1, ARFGEF1, NCL, GZMH, CSNK2B, CSNK2A1, HCVgp1, CBX6, SPIB, IL7R, IFIT3, FN1, SMURF1, BARD1, PAXIP1, APP, TROVE2, XIAP, CAN
Protein Size: 408

分子量

45 kDa

基因ID

6741

NCBI登录号

NM_003142, NP_003133

UniProt

P05455