ISG20 抗体 (N-Term)
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- 抗原 See all ISG20 抗体
- ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠, 犬, 马, Cow, Pig, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ISG20 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20
- Top Product
- Discover our top product ISG20 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 181 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).
: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).
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HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).
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- 抗原
- ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))
- 别名
- ISG20 (ISG20 产品)
- 别名
- ISG20 antibody, CD25 antibody, HEM45 antibody, 1600023I01Rik antibody, 2010107M23Rik antibody, 20kDa antibody, DnaQL antibody, interferon stimulated exonuclease gene 20 antibody, interferon-stimulated protein antibody, ISG20 antibody, Isg20 antibody
- 背景
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ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
Alias Symbols: CD25, HEM45
Protein Interaction Partner: UBC,
Protein Size: 181 - 分子量
- 20 kDa
- 基因ID
- 3669
- NCBI登录号
- NM_002201, NP_002192
- UniProt
- Q96AZ6
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