HNRNPA1 抗体 (N-Term)
(4 references)-
- 抗原 See all HNRNPA1 抗体
- HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HNRNPA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MSKSESPKEP EQLRKLFIGG LSFETTDESL RSHFEQWGTL TDCVVMRDPN
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HNRPA1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPA1
- Top Product
- Discover our top product HNRNPA1 Primary Antibody
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anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 2-372) antibody
HNRNPA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 1-372) antibodyHNRNPA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibodyHNRNPA1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibodyKO Validated HNRNPA1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibodyHNRNPA1 适用: 人, 小鼠 WB, ELISA, IF, IP, IHC (p), ICC, FACS 宿主: 小鼠 Monoclonal 9H10 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 8-42), (N-Term) antibodyHNRNPA1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 1-320) antibodyHNRNPA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 8-42) antibodyHNRNPA1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (AA 2-354) antibodyHNRNPA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) (N-Term) antibodyHNRNPA1 适用: 人, 小鼠, 大鼠, 猴, 犬, Cow, Pig, 马, 兔, 豚鼠, 小鸡, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 320 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Aptamer BC15 against heterogeneous nuclear ribonucleoprotein A1 has potential value in diagnosis and therapy of hepatocarcinoma." in: Nucleic acid therapeutics, Vol. 22, Issue 6, pp. 391-8, (2012) (PubMed).
: "Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance." in: The Journal of biological chemistry, Vol. 286, Issue 5, pp. 3741-54, (2011) (PubMed).
: "The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 33602-13, (2010) (PubMed).
: "Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX." in: The Journal of pathology, Vol. 218, Issue 3, pp. 327-36, (2009) (PubMed).
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: "Aptamer BC15 against heterogeneous nuclear ribonucleoprotein A1 has potential value in diagnosis and therapy of hepatocarcinoma." in: Nucleic acid therapeutics, Vol. 22, Issue 6, pp. 391-8, (2012) (PubMed).
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- 抗原
- HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))
- 别名
- HNRPA1 (HNRNPA1 产品)
- 别名
- HNRPA1 antibody, HNRPA1L3 antibody, hnRNP A1 antibody, hnRNP-A1 antibody, hnrpa1 antibody, TPT1P antibody, HNRNPA1 antibody, D15Ertd119e antibody, Hdp antibody, Hnrpa1 antibody, hnrnp-A1 antibody, ROA1 antibody, zgc:66127 antibody, heterogeneous nuclear ribonucleoprotein A1 antibody, heterogeneous nuclear ribonucleoprotein A1b antibody, Heterogeneous nuclear ribonucleoprotein A1 antibody, heterogeneous nuclear ribonucleoprotein A1 S homeolog antibody, ribonucleoprotein A1a antibody, heterogeneous nuclear ribonucleoprotein A1-like antibody, heterogeneous nuclear ribonucleoprotein A1a antibody, HNRNPA1 antibody, hnrnpa1b antibody, LOC100101226 antibody, roa1 antibody, Hnrnpa1 antibody, hnrnpa1.S antibody, hnrnpa1 antibody, LOC100359118 antibody, hnrnpa1a antibody
- 背景
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HNRPA1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). HNRPA1 has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. HNRPA1 is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.
Alias Symbols: HNRPA1, HNRPA1L3, hnRNP A1, hnRNP-A1
Protein Interaction Partner: UBC, TP53, PSMD9, TUBGCP3, NEDD1, AURKB, AURKA, STAU1, IVNS1ABP, TNF, PSMB4, MDM2, CHUK, RPA3, RPA2, RPA1, ASB2, ERG, EED, RNF2, rev, IQGAP1, HIST1H2AB, AIMP2, RPL38, RPL27A, QARS, DHX9, CCAR2, ZC3HC1, HNRNPU, PARK2, FBXO6, TARDBP, YWHAQ, SRPK1, XRN1, CSF
Protein Size: 320 - 分子量
- 35 kDa
- 基因ID
- 3178
- NCBI登录号
- NM_002136, NP_002127
- UniProt
- Q6IPF2
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