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Fibrillarin 抗体 (N-Term)

Name: Fibrillarin 抗体 (N-Term)
SKU: ABIN2778775
Availability: OutOfStock

FBL 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-FBL Antibody Titration: 1. (Fibrillarin 抗体 (N-Term))

Rabbit Anti-FBL Antibody Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4. (Fibrillarin 抗体 (N-Term))

IHC

3 images

(2 references)

产品编号 ABIN2778775

发货至: 中国

Datasheet as PDF

抗原 See all Fibrillarin (FBL) 抗体

Fibrillarin (FBL)
抗原表位
3

3

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
48

29

28

3

2

2

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔
宿主
41

10

1
兔
Compatible Secondaries
克隆类型
41

11
多克隆
标记
31

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Fibrillarin antibody is un-conjugated
应用范围
43

12

10

9

8

5

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

GGGFHSGGNR GRGRGGKRGN QSGKNVMVEP HRHEGVFICR GKEDALVTKN

预测反应

Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against FBL. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human FBL

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FBL 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: Saccharomyces cerevisiae WB, IF 宿主: 小鼠 Monoclonal 38F3 unconjugated

anti-Fibrillarin (FBL) (AA 1-321) antibody
FBL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G9-E4 unconjugated

anti-Fibrillarin (FBL) (Internal Region) antibody
FBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (AA 61-110) antibody
FBL 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (N-Term) antibody
FBL 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: 人, 小鼠, 猴 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (AA 85-274) antibody
FBL 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 321 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Ernoult-Lange, Wilczynska, Harper, Aigueperse, Dautry, Kress, Weil: "Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies." in: Molecular biology of the cell, Vol. 20, Issue 1, pp. 176-87, (2009) (PubMed).

Armistead, Khatkar, Meyer, Mark, Patel, Coghlan, Lamont, Liu, Wiechert, Cattini, Koetter, Wrogemann, Greenberg, Entian, Zelinski, Triggs-Raine: "Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome." in: American journal of human genetics, Vol. 84, Issue 6, pp. 728-39, (2009) (PubMed).
抗原

Fibrillarin (FBL)

别名

FBL (FBL 产品)

背景

FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
Alias Symbols: FIB, FLRN, RNU3IP1
Protein Interaction Partner: UBC, CEP250, TP53, SUMO2, SUMO3, LIN28A, LIN28B, RPA3, RPA2, RPA1, ERG, RNF2, BMI1, SUZ12, EED, EZH2, TARDBP, UBD, NCL, ARFGEF1, PAN2, CBX8, ITGA4, FN1, VCAM1, MAGOH, EIF4A3, EEF1A1, DHX15, NSUN2, NOP58, MRTO4, GNL3, RSL1D1, SRRM2, BOP1, RRS1, EBNA1BP2, P
Protein Size: 321

分子量

35 kDa

基因ID

2091

NCBI登录号

NM_001436, NP_001427

UniProt

P22087

途径

Ribonucleoside Biosynthetic Process