CSH1 抗体 (Middle Region)
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- 抗原 See all CSH1 抗体
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CSH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- SMFANNLVYD TSDSDDYHLL KDLEEGIQTL MGRLEDGSRR TGQILKQTYS
- 预测反应
- Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CSH1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CSH1
- Top Product
- Discover our top product CSH1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 217 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))
- 别名
- CSH1 (CSH1 产品)
- 别名
- CS-1 antibody, CSA antibody, CSMT antibody, PL antibody, hCS-A antibody, CS-2 antibody, CSB antibody, hCS-B antibody, chorionic somatomammotropin hormone 1 antibody, chorionic somatomammotropin hormone 2 antibody, CSH1 antibody, CSH2 antibody
- 背景
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CSH1 is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Alias Symbols: PL, CSA, CS-1, CSMT, hCS-A
Protein Interaction Partner: PSMD9, PTPN12, SMAD9, SMAD4, SMAD2, PRLR, POLR2A, SMAD3,
Protein Size: 217 - 分子量
- 24 kDa
- 基因ID
- 1442
- NCBI登录号
- NM_001317, NP_001308
- UniProt
- P01243
- 途径
- Response to Growth Hormone Stimulus
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