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SNRNP70 抗体 (N-Term)

SNRNP70 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778715
发货至: 中国
  • 抗原 See all SNRNP70 抗体
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    抗原表位
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 18
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 兔, 马
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNRNP70 antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70
    Top Product
    Discover our top product SNRNP70 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 437 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

    Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

  • 抗原
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    别名
    SNRP70 (SNRNP70 产品)
    背景
    SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
    Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
    Protein Size: 437
    分子量
    52 kDa
    基因ID
    6625
    NCBI登录号
    NM_003089, NP_003080
    UniProt
    P08621
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