SF3B1 抗体 (N-Term)
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- 抗原 See all SF3B1 抗体
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SF3B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MAKIAKTHED IEAQIREIQG KKAALDEAQG VGLDSTGYYD QEIYGGSDSR
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against SF3B1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B1
- Top Product
- Discover our top product SF3B1 Primary Antibody
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anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibody
SF3B1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibodySF3B1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 6C7 unconjugated Recombinant Antibody
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 1-144) antibodySF3B1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 186-378) antibodySF3B1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 374-402), (N-Term) antibodySF3B1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33758 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 98-198) antibodySF3B1 适用: 人, 小鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 16 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1304 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- 别名
- SF3B1 (SF3B1 产品)
- 别名
- Cus1 antibody, SAP145 antibody, SF3B145 antibody, SF3b1 antibody, SF3b150 antibody, Hsh155 antibody, MDS antibody, PRP10 antibody, PRPF10 antibody, SAP155 antibody, SF3b155 antibody, 155kDa antibody, 2810001M05Rik antibody, AA409119 antibody, Prp10 antibody, TA-8 antibody, Targ4 antibody, hsh155 antibody, prp10 antibody, prpf10 antibody, sap155 antibody, SF3B1 antibody, Sap155 antibody, wu:fb99f09 antibody, splicing factor 3b subunit 2 antibody, splicing factor 3b subunit 1 antibody, splicing factor 3b, subunit 1 antibody, splicing factor 3b subunit 1 S homeolog antibody, SF3B2 antibody, SF3B1 antibody, Sf3b1 antibody, sf3b1.S antibody, sf3b1 antibody
- 背景
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SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PRP10, SAP155, SF3b155, MDS, Hsh155, PRPF10
Protein Interaction Partner: SART3, SUMO2, SUMO3, MDM2, STAU1, UBC, LGR4, WWOX, RPA3, RPA2, RPA1, ERG, EED, RNF2, EZH2, SUZ12, APBB1, PRPF40A, WBP4, TCERG1, FBXO6, RBM17, SNIP1, SF3B6, WHSC1, RPS2, RPL23A, RPL18A, RPL10, RPL3, PLRG1, SMAD9, SMAD5, SMAD1, IL7R, FN1, ESR1, CSNK2A1, EIF
Protein Size: 1304 - 分子量
- 143 kDa
- 基因ID
- 23451
- NCBI登录号
- NM_012433, NP_036565
- UniProt
- O75533
- 途径
- Chromatin Binding
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