HNRNPD/AUF1 抗体 (C-Term)
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- 抗原 See all HNRNPD/AUF1 (HNRNPD) 抗体
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HNRNPD/AUF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- YGYNSQGYGG YGGYDYTGYN NYYGYGDYSN QQSGYGKVSR RGGHQNSYKP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against HNRPD. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPD
- Top Product
- Discover our top product HNRNPD Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 355 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3'-untranslated region." in: Cancer letters, Vol. 297, Issue 2, pp. 259-68, (2010) (PubMed).
: "Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells." in: Oncogene, Vol. 28, Issue 4, pp. 565-74, (2009) (PubMed).
: "cAMP-dependent stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ kidney cells." in: American journal of physiology. Renal physiology, Vol. 290, Issue 2, pp. F313-8, (2006) (PubMed).
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Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3'-untranslated region." in: Cancer letters, Vol. 297, Issue 2, pp. 259-68, (2010) (PubMed).
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- 抗原
- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
- 别名
- HNRPD (HNRNPD 产品)
- 别名
- AUF1 antibody, AUF1A antibody, HNRPD antibody, P37 antibody, hnRNPD0 antibody, Auf1 antibody, Hnrnpd antibody, HNRNPD antibody, p37 antibody, auf1a antibody, hnrpd antibody, hnrnpd0 antibody, C230004L04 antibody, Hnrpd antibody, wu:fa28b06 antibody, zgc:162951 antibody, heterogeneous nuclear ribonucleoprotein D antibody, heterogeneous nuclear ribonucleoprotein D L homeolog antibody, HNRNPD antibody, Hnrnpd antibody, hnrnpd antibody, hnrnpd.L antibody
- 背景
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HNRPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Alias Symbols: P37, AUF1, AUF1A, HNRPD, hnRNPD0
Protein Interaction Partner: NCL, FUS, KAT2B, SUMO2, SUMO3, IVNS1ABP, STAU1, UBC, NEDD8, MDM2, ERG, RPA3, RPA2, RPA1, ASB2, EED, rev, ERI1, RPS12, PTBP1, PAFAH1B3, WNK1, IPO11, EIF3K, KHSRP, DENR, PARK2, DGCR2, GTF3C3, PDLIM7, UQCRC1, HIRA, SNAPC4, SLC3A2, SDF2, COG7, TMEM261, ABCC10
Protein Size: 355 - 分子量
- 39 kDa
- 基因ID
- 3184
- NCBI登录号
- NM_031370, NP_112738
- UniProt
- Q14103
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