PRMT7 抗体 (C-Term)
-
- 抗原 See all PRMT7 抗体
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠, 马, 犬, 豚鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PRMT7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- GEINDQDRTD HYAQALRTVL LPGSVCLCVS DGSLLSMLAH HLGAEQVFTV
- 预测反应
- Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against Prmt7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product PRMT7 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 692 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
- 别名
- Prmt7 (PRMT7 产品)
- 别名
- ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 antibody, ATPRMT7 antibody, DL4310W antibody, FCAALL.195 antibody, protein arginine methyltransferase 7 antibody, RGD1304869 antibody, 4933402B05Rik antibody, BC006705 antibody, zgc:66172 antibody, protein arginine methyltransferase 7 antibody, protein arginine methyltransferase 7 L homeolog antibody, protein arginine N-methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody, PRMT7 antibody, Prmt7 antibody, prmt7.L antibody, prmt7 antibody, prmt-7 antibody
- 背景
-
Prmt7 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. It specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. It plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. It may also play a role in embryonic stem cell (ESC) pluripotency. It also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Alias Symbols: 4933402B05Rik, BC006705, MGC7929
Protein Interaction Partner: Ctcfl,
Protein Size: 692 - 分子量
- 78 kDa
- 基因ID
- 214572
- NCBI登录号
- NM_145404, NP_663379
- UniProt
- Q922X9
- 途径
- Ribonucleoprotein Complex Subunit Organization
-