PRMT5 抗体 (N-Term)
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- 抗原 See all PRMT5 抗体
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, 马, Cow, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRMT5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- FDFLCMPVFH PRFKREFIQE PAKNRPGPQT RSDLLLSGRD WNTLIVGKLS
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
- 产品特性
- This is a rabbit polyclonal antibody against PRMT5. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRMT5
- Top Product
- Discover our top product PRMT5 Primary Antibody
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anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 40-140) antibody
PRMT5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (Internal Region) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 21-70) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, 猴, 豚鼠, Bat, Pig, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 297-534) antibodyPRMT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠 WB, IHC, IF, IP, ChIP, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 76-104) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 591-621) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 620 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
- 别名
- PRMT5 (PRMT5 产品)
- 背景
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PRMT5 methylates specific arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3 to monomethylarginine and to symmetrical dimethylarginines (sDMAs). It methylates SUPT5H. PRMT5 plays a role in the assembly of snRNP core particles and may play a role in cytokine-activated transduction pathways. It negatively regulates cyclin E1 promoter activity and cellular proliferation and May regulate the SUPT5H transcriptional elongation properties. It may be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. PRMT5 methylates histone H2A/H4 'Arg-3' during germ cell development and methylates histone H3 'Arg-8', which may repress transcription.
Alias Symbols: JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5
Protein Interaction Partner: UBC, TP53, ING2, PRDM1, NFE4, WDR5, SUMO2, WWOX, CDYL2, LENG8, LDHAL6B, PRPF38A, ING5, ZNF436, WDR77, GRHL3, TRIB3, RSRP1, LUC7L, RBM23, GTPBP2, H3F3C, FOXK1, ZUFSP, FAM76B, NUDCD2, MAGEB2, NELFCD, COPS4, COPS7A, DCAF8, SPAG8, SLU7, MCRS1, CUL4A, ZNF2, YW
Protein Size: 620 - 分子量
- 68 kDa
- 基因ID
- 10419
- NCBI登录号
- NM_001039619, NP_001034708
- UniProt
- O14744
- 途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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