INSIG2 抗体 (N-Term)
(1 reference)-
- 抗原 See all INSIG2 抗体
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 兔, Cow, 山羊, 马, Pig, 犬, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INSIG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MAEGETESPG PKKCGPYISS VTSQSVNLMI RGVVLFFIGV FLALVLNLLQ
- 预测反应
- Cow: 100%, Dog: 92%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against INSIG2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human INSIG2
- Top Product
- Discover our top product INSIG2 Primary Antibody
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anti-Insulin Induced Gene 2 (INSIG2) (AA 50-150) antibody
INSIG2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) antibodyINSIG2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 兔, Cow, 山羊, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 225 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 70, Issue 4, pp. 410-20, (2015) (PubMed).
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: "Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 70, Issue 4, pp. 410-20, (2015) (PubMed).
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- 抗原
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- 别名
- INSIG2 (INSIG2 产品)
- 别名
- MGC82156 antibody, INSIG-2 antibody, 2900053I11Rik antibody, C730043J18Rik antibody, Insig-2 antibody, insulin induced gene 2 antibody, insulin induced gene 2 L homeolog antibody, insig2 antibody, insig2.L antibody, INSIG2 antibody, Insig2 antibody
- 背景
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INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC26273
Protein Interaction Partner: RNF5, HMGCR, SCAP, SREBF1, RNF139, UBQLN1, UBQLN2, FAF2, ADRM1, PSMD14, BAG6, VCP, UBC, RPN1, PSMD13, PSMD12, PSMD11, PSMD4, PSMC6, PSMC5, PSMC3, PSMC2, PSMB3, PSMB1, PSMA7, PSMA2, LGALS7, JUP, INSIG1, HSPA8, HSPA6, HSPA5, HSPA1A, ENO1, DSP, AMFR, SREBF2,
Protein Size: 225 - 分子量
- 25 kDa
- 基因ID
- 51141
- NCBI登录号
- NM_016133, NP_057217
- UniProt
- Q9Y5U4
- 途径
- ER-Nucleus Signaling
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