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RNF34 抗体 (Middle Region)

RNF34 适用: 人, 大鼠, Cow, 犬, 兔, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501925
发货至: 中国
  • 抗原 See all RNF34 抗体
    RNF34 (Ring Finger Protein 34 (RNF34))
    抗原表位
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Middle Region
    适用
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Cow, 犬, 兔, 马, 豚鼠
    宿主
    • 21
    • 2
    • 1
    克隆类型
    • 24
    多克隆
    标记
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF34 antibody is un-conjugated
    应用范围
    • 22
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LVDLVLCHHG LGSEDDMDTS SLNSSRSQTS SFFTRSFFSN YTAPSATMSS
    预测反应
    Cow: 87%, Dog: 93%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Rabbit: 80%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against RNF34. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human RNF34
    Top Product
    Discover our top product RNF34 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 372 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RNF34 (Ring Finger Protein 34 (RNF34))
    别名
    RNF34 (RNF34 产品)
    背景
    RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis.The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: FLJ21786, RFI, RIF, RIFF, hRFI, CARP1, CARP-1
    Protein Interaction Partner: APPBP2, NOD1, APP, PRKACB, PHF7, TRIM23, UBE2D2, CASP10, CASP8, FZR1, ANAPC2, CDC20, SH3KBP1, PPARGC1A, TP53, UBE2F, UBE2H, DNAJA3,
    Protein Size: 372
    分子量
    42 kDa
    基因ID
    80196
    NCBI登录号
    NM_025126, NP_079402
    UniProt
    Q969K3
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