Aprataxin 抗体 (C-Term)
(1 reference)-
- 抗原 See all Aprataxin (APTX) 抗体
- Aprataxin (APTX)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aprataxin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ
- 预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against APTX. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human APTX
- Top Product
- Discover our top product APTX Primary Antibody
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anti-Aprataxin (APTX) (AA 69-166) antibody
APTX 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Aprataxin (APTX) (AA 93-342) antibodyAPTX 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 1-254) antibodyAPTX 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Aprataxin (APTX) (C-Term) antibodyAPTX 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 猴, Pig, Bat, Hamster IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) antibodyAPTX 适用: 人, 小鼠, 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 92-161) antibodyAPTX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (N-Term) antibodyAPTX 适用: 人, 豚鼠, 犬, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (AA 108-157) antibodyAPTX 适用: 人, 豚鼠, 犬, Cow, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aprataxin (APTX) (N-Term) antibodyAPTX 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 342 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2375-82, (2010) (PubMed).
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: "Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2375-82, (2010) (PubMed).
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- 抗原
- Aprataxin (APTX)
- 别名
- APTX (APTX 产品)
- 别名
- aptx antibody, APTX antibody, LOC100284636 antibody, APRATAXIN-like antibody, T10O8.20 antibody, T10O8_20 antibody, AOA antibody, AOA1 antibody, AXA1 antibody, EAOH antibody, EOAHA antibody, FHA-HIT antibody, 2410016G21Rik antibody, AA388047 antibody, aprataxin antibody, FHA-HIT antibody, APRATAXIN-like protein antibody, aprataxin L homeolog antibody, aptx antibody, APTX antibody, CpipJ_CPIJ001673 antibody, LOC100284636 antibody, aptx.L antibody, Aptx antibody
- 背景
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APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Alias Symbols: AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT
Protein Interaction Partner: PNMA1, UBC, SUMO1, NEDD8, LIG3, HSPA4, XRCC1, DDX21, CNTROB, TSPYL2, CALCOCO1, SYT17, ZNF639, MAPKBP1, CEP350, PICK1, XRCC4, TRIM37, MBP, HIVEP1, BANF1, PARP1, TP53,
Protein Size: 342 - 分子量
- 38 kDa
- 基因ID
- 54840
- NCBI登录号
- NM_175073, NP_778243
- UniProt
- Q6JV85
- 途径
- DNA Damage Repair, Chromatin Binding
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