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MED17 抗体 (N-Term)

MED17 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182953
发货至: 中国
  • 抗原 See all MED17 抗体
    MED17 (Mediator Complex Subunit 17 (MED17))
    抗原表位
    • 16
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 49
    • 26
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 47
    • 4
    克隆类型
    • 48
    • 3
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED17 antibody is un-conjugated
    应用范围
    • 44
    • 26
    • 14
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
    序列
    AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
    Top Product
    Discover our top product MED17 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 651 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MED17 (Mediator Complex Subunit 17 (MED17))
    别名
    CRSP6 (MED17 产品)
    背景
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
    Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
    Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
    Protein Size: 651
    分子量
    73 kDa
    基因ID
    9440
    NCBI登录号
    NM_004268, NP_004259
    UniProt
    Q9NVC6
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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