MED17 抗体 (N-Term)
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- 抗原 See all MED17 抗体
- MED17 (Mediator Complex Subunit 17 (MED17))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- 序列
- AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
- Top Product
- Discover our top product MED17 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 651 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MED17 (Mediator Complex Subunit 17 (MED17))
- 别名
- CRSP6 (MED17 产品)
- 别名
- crsp6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, TRAP80 antibody, 77kDa antibody, C330002H14Rik antibody, Crsp6 antibody, Trap80 antibody, mediator of RNA polymerase II transcription subunit 17 antibody, mediator complex subunit 17 antibody, mediator complex subunit 17 L homeolog antibody, AOR_1_2446154 antibody, VDBG_01663 antibody, med17 antibody, med17.L antibody, MED17 antibody, Med17 antibody
- 背景
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651 - 分子量
- 73 kDa
- 基因ID
- 9440
- NCBI登录号
- NM_004268, NP_004259
- UniProt
- Q9NVC6
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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