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TIMELESS 抗体 (N-Term)

TIMELESS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182949
发货至: 中国
  • 抗原 See all TIMELESS 抗体
    TIMELESS (Timeless Homolog (TIMELESS))
    抗原表位
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 33
    • 16
    • 12
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔
    宿主
    • 33
    • 3
    • 1
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 30
    • 4
    • 2
    • 1
    This TIMELESS antibody is un-conjugated
    应用范围
    • 29
    • 14
    • 9
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    IGERDLIFHK GLHNLRNYSS DLGKQPKKVP KRRQAARELS IQRRSALNVR
    预测反应
    Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 77%, Rat: 85%, Sheep: 77%
    产品特性
    This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human TIMELESS
    Top Product
    Discover our top product TIMELESS Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1208 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TIMELESS (Timeless Homolog (TIMELESS))
    别名
    TIMELESS (TIMELESS 产品)
    背景
    The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
    Alias Symbols: TIM, TIM1, hTIM
    Protein Interaction Partner: UBC, TUT1, TF, XRCC1, FKBP3, SP1, SUMO2, Tipin, Timeless, ZSCAN1, PCBD1, CRY1, PER2, PER1, CLSPN, PCNA, per, Clock, ATRIP, CRY2, CHEK1,
    Protein Size: 1208
    分子量
    139 kDa
    基因ID
    8914
    NCBI登录号
    NM_003920, NP_003911
    UniProt
    Q9UNS1
    途径
    Protein targeting to Nucleus, Photoperiodism
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