NCOA1 抗体 (Middle Region)
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- 抗原 See all NCOA1 抗体
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GLLHNNDRLS DGDSKYSQTS HKLVQLLTTT AEQQLRHADI DTSCKDVLSC
- 预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NCOA1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NCOA1
- Top Product
- Discover our top product NCOA1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1399 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
- 别名
- NCOA1 (NCOA1 产品)
- 背景
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NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. NCOA1 binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: F-SRC-1, KAT13A, MGC129719, MGC129720, NCoA-1, RIP160, SRC1, bHLHe42, bHLHe74
Protein Interaction Partner: ASCC1, NR1I2, PPARG, AR, VDR, THRB, RXRA, RORB, RORA, RARA, HNF4G, NR6A1, NR5A2, ESRRA, ESR1, PAGR1, Esr2, NR3C1, CXADR, PPARA, AHR, KANK2, NCOA2, TRIM24, NCOA1, ANIB1, PGR, COPS5, UBE2L3, TP53, NCOA6, EP300, UBC, RARB, PPARD, RARG, RBBP6, CREBBP, STAT3,
Protein Size: 1399 - 分子量
- 152 kDa
- 基因ID
- 8648
- NCBI登录号
- NM_147223, NP_671756
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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