Kallikrein 6 抗体 (N-Term)
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- 抗原 See all Kallikrein 6 (KLK6) 抗体
- Kallikrein 6 (KLK6)
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抗原表位
- N-Term
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适用
- 人, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kallikrein 6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- KHNLRQRESS QEQSSVVRAV IHPDYDAASH DQDIMLLRLA RPAKLSELIQ
- 预测反应
- Dog: 92%, Horse: 92%, Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KLK6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6
- Top Product
- Discover our top product KLK6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 244 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Kallikrein 6 (KLK6)
- 别名
- KLK6 (KLK6 产品)
- 别名
- Bssp antibody, Klk7 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, Prss9 antibody, AI849898 antibody, BSP antibody, Klk29 antibody, MSP antibody, Prss18 antibody, neurosin antibody, kallikrein related peptidase 6 antibody, kallikrein related-peptidase 6 antibody, kallikrein-6 antibody, KLK6 antibody, Klk6 antibody, LOC100716801 antibody
- 背景
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6
Protein Interaction Partner: SNCA, SERPINF2, SERPINC1,
Protein Size: 244 - 分子量
- 25 kDa
- 基因ID
- 5653
- NCBI登录号
- NM_001012964, NP_001012982
- UniProt
- Q92876
- 途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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